Molecular Formula | C11H21N3O3 |
Molar Mass | 243.3 |
Density | 1.147±0.06 g/cm3(Predicted) |
Melting Point | 104-106°C |
Boling Point | 409.2±34.0 °C(Predicted) |
Flash Point | 201.291°C |
Vapor Presure | 0mmHg at 25°C |
pKa | 13.01±0.20(Predicted) |
Storage Condition | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
Refractive Index | 1.508 |
Risk Codes | 22 - Harmful if swallowed |
Hazard Class | IRRITANT |
uses | ethyl N-Boc-4-piperidine formate is a key intermediate in the synthesis of sodium channel blockers, which is used to treat stroke patients. It is also used as a key intermediate in the preparation of tumor necrosis factor converting enzyme inhibitors. It is also a key intermediate for the synthesis of 1-BOC-4-piperidinyl hydrazide. |
Preparation | Using N-Boc-4-piperidine ethyl formate or N-Boc-4-piperidine methyl formate as the starting material, it is combined with hydrazine hydrate or bis-(1H-Imidazol-2-yl)-methanone is reacted to prepare the target compound 1-BOC-4-piperidinylhydrazine [1]. The synthesis reaction formula of 1-BOC-4-piperidinylhydrazide is as follows: fig. 1 the synthesis reaction formula of 1-BOC-4-piperidinylhydrazide |